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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70982
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsk3b
Name: glycogen synthase kinase 3 beta
Acc ID: CHEBI:68798
Term: chaetoglobosin A
Definition: A cytochalasan alkaloid isolated from Chaetomium globosum and Calonectria morganii.
Chemical ID: MESH:C019290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsk3bincreases phosphorylationEXP 6480464CTDchaetoglobosins results in increased phosphorylation of GSK3B proteinPMID:18040759
Gsk3bmultiple interactionsEXP 6480464CTDwortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]PMID:18040759
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