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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:68798
Term: chaetoglobosin A
Definition: A cytochalasan alkaloid isolated from Chaetomium globosum and Calonectria morganii.
Chemical ID: MESH:C019290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases phosphorylationEXP 6480464CTDchaetoglobosins results in increased phosphorylation of MAPK3 proteinPMID:18040759
Mapk3multiple interactionsISOMapk3 (Mus musculus)6480464CTDchaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]PMID:33285210
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