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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcat
Name: lecithin cholesterol acyltransferase
Acc ID: CHEBI:68657
Term: zingerone
Definition: A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger.
Chemical ID: MESH:C013738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcatmultiple interactionsEXP 6480464CTDzingerone inhibits the reaction [Ethanol results in decreased activity of LCAT protein]PMID:28442378
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