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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1619215 Species: Mus musculus RGD Object: Gene Symbol: Cyp3a41a Name: cytochrome P450, family 3, subfamily a, polypeptide 41A

Acc ID: CHEBI:6820 Term: methapyrilene Definition: A member of the class of ethylenediamine derivatives that is ethylenediamine in which one of the nitrogens is substituted by two methyl groups, and the other nitrogen is substituted by a 2-pyridyl group and a (2-thienyl)methyl group. CasRN: 91-80-5 Chemical ID: MESH:D008701

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:628626	6480464	CTD	Methapyrilene results in decreased expression of CYP3A23/3A1 mRNA	PMID:15120968