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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736736
Species: Homo sapiens
RGD Object: Gene
Symbol: AANAT
Name: aralkylamine N-acetyltransferase
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AANATdecreases expressionISOAanat (Rattus norvegicus)6480464CTDMethamphetamine results in decreased expression of AANAT mRNAPMID:19149911
AANATmultiple interactionsISOAanat (Rattus norvegicus)6480464CTDLithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]PMID:19149911
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