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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735751 Species: Homo sapiens RGD Object: Gene Symbol: MAOA Name: monoamine oxidase A

Acc ID: CHEBI:6809 Term: methamphetamine Definition: An amphetamine that has formula C10H15N. CasRN: 537-46-2 Chemical ID: MESH:D008694

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:61898	6480464	CTD	Methamphetamine results in increased expression of MAOA mRNA	PMID:19149911
affects response to substance	ISO	RGD:62191	6480464	CTD	MAOA protein affects the susceptibility to Methamphetamine	PMID:1905457
multiple interactions	ISO	RGD:62191	6480464	CTD	[Clorgyline results in decreased activity of MAOA protein] which results in increased susceptibility to Methamphetamine	PMID:1905457