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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71009
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adcy3
Name: adenylate cyclase 3
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adcy3decreases expressionISOAdcy3 (Mus musculus)6480464CTDMethamphetamine results in decreased expression of ADCY3 mRNAPMID:11756511
Adcy3multiple interactionsISOAdcy3 (Mus musculus)6480464CTD(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ADCY3 mRNA]PMID:11756511
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