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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621871 Species: Rattus norvegicus RGD Object: Gene Symbol: Mt-co1 Name: mitochondrially encoded cytochrome c oxidase I

Acc ID: CHEBI:6809 Term: methamphetamine Definition: An amphetamine that has formula C10H15N. CasRN: 537-46-2 Chemical ID: MESH:D008694

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:736621	6480464	CTD	Methamphetamine results in increased expression of COX1 mRNA	PMID:11756511
multiple interactions	ISO	RGD:736621	6480464	CTD	(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in increased expression of COX1 mRNA]	PMID:11756511