GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | Methamphetamine results in increased expression of BAX protein | PMID:19149911 PMID:26524635 PMID:26923100 PMID:31059759 PMID:32035215 PMID:34214594 | Bax | multiple interactions | EXP | | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein] | PMID:19149911 PMID:26524635 PMID:31059759 PMID:32035215 PMID:34214594 | Bax | increases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein | PMID:26307267 PMID:29467000 PMID:31422080 PMID:32203791 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein | PMID:23820845 PMID:26524635 PMID:31059759 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein] | PMID:29467000 PMID:31422080 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein] | PMID:23820845 PMID:26524635 PMID:31059759 PMID:32203791 | | ||||||||||||||||||||||
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