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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2200
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2l1
Name: Bcl2-like 1
Acc ID: CHEBI:6801
Term: metformin
Definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chemical ID: MESH:D008687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1multiple interactionsEXP 6480464CTDMetformin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]PMID:35414346
Bcl2l1decreases expressionISOBCL2L1 (Homo sapiens)6480464CTDMetformin results in decreased expression of BCL2L1 proteinPMID:21388661
Bcl2l1multiple interactionsISOBCL2L1 (Homo sapiens)6480464CTDCisplatin promotes the reaction [Metformin results in decreased expression of BCL2L1 protein]PMID:21388661
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