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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563119 Species: Rattus norvegicus RGD Object: Gene Symbol: Mef2c Name: myocyte enhancer factor 2C

Acc ID: CHEBI:6801 Term: metformin Definition: A guanidine that has formula C4H11N5. CasRN: 657-24-9 Chemical ID: MESH:D008687

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1349172	6480464	CTD	Metformin results in increased expression of MEF2C mRNA	PMID:15864539