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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:66960
Term: olivetol
Definition: A member of the class of resorcinols that is resorcinol in which the hydrogen at position 5 is replaced by a pentyl group.
Chemical ID: MESH:C016630
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1decreases activityISOCYP1A1 (Homo sapiens)6480464CTDolivetol results in decreased activity of CYP1A1 proteinPMID:24667653
Cyp1a1increases expressionISOCYP1A1 (Homo sapiens)6480464CTDolivetol results in increased expression of CYP1A1 mRNAPMID:26187180
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