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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730893 Species: Mus musculus RGD Object: Gene Symbol: Nfkb1 Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

Acc ID: CHEBI:6682 Term: mangiferin Definition: A C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. CasRN: 4773-96-0 Chemical ID: MESH:C013592

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:730892	6480464	CTD	mangiferin inhibits the reaction [TNF protein affects the localization of and results in increased activity of NFKB1 protein]	PMID:15161907