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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733147
Species: Mus musculus
RGD Object: Gene
Symbol: Tjp2
Name: tight junction protein 2
Acc ID: CHEBI:6649
Term: malaoxon
Definition: A racemate comprising equimolar amounts of (R) and (S)-malaoxon. It is the active insecticide of the proinsecticide malathion.
Chemical ID: MESH:C100082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tjp2decreases expressionISOTjp2 (Rattus norvegicus)6480464CTDmalaoxon results in decreased expression of TJP2 proteinPMID:20970449
Tjp2multiple interactionsISOTjp2 (Rattus norvegicus)6480464CTD[malaoxon co-treated with Lead] results in decreased expression of TJP2 proteinPMID:20970449
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