GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | decreases expression | EXP | | 6480464 | CTD | Losartan results in decreased expression of CCL2 mRNA; Losartan results in decreased expression of CCL2 protein | PMID:10925121 PMID:17922026 | Ccl2 | multiple interactions | EXP | | 6480464 | CTD | Losartan inhibits the reaction [Estrogens deficiency results in increased expression of CCL2 protein]; Losartan inhibits the reaction [Ethylene Glycol results in increased expression of CCL2 protein]; Losartan inhibits the reaction [glyoxylic acid results in increased expression of CCL2 protein] | PMID:16284884 PMID:19553526 PMID:37454925 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Losartan inhibits the reaction [AGT protein results in increased expression of CCL2 protein] | PMID:28578904 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Losartan inhibits the reaction [AGT protein results in increased expression of CCL2 protein] | PMID:28578904 | |
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