GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ace | decreases expression | EXP | | 6480464 | CTD | Losartan results in decreased expression of ACE protein | PMID:28091615 | Ace | decreases expression | ISO | Ace (Mus musculus) | 6480464 | CTD | Losartan results in decreased expression of ACE protein | PMID:25655897 | Ace | multiple interactions | ISO | Ace (Mus musculus) | 6480464 | CTD | Losartan inhibits the reaction [AGT protein results in increased expression of ACE mRNA]; Losartan inhibits the reaction [AGT protein results in increased expression of ACE protein]; Losartan inhibits the reaction [Oxygen deficiency results in increased expression of ACE protein]; Losartan inhibits the reaction [Silicon Dioxide results in increased expression of ACE mRNA]; Losartan inhibits the reaction [Silicon Dioxide results in increased expression of ACE protein] | PMID:25511041 PMID:28578904 PMID:33007385 | Ace | multiple interactions | ISO | ACE (Homo sapiens) | 6480464 | CTD | Losartan inhibits the reaction [AGT protein results in increased expression of ACE protein] | PMID:28578904 | | ||||||||||||||||||||||
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