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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289 Species: Mus musculus RGD Object: Gene Symbol: Casp3 Name: caspase 3

Acc ID: CHEBI:6541 Term: losartan Definition: A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position CasRN: 114798-26-4 Chemical ID: MESH:D019808

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases cleavage	ISO	RGD:2275	6480464	CTD	Losartan results in increased cleavage of CASP3 protein	PMID:12623880