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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2665
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gata4
Name: GATA binding protein 4
Acc ID: CHEBI:64317
Term: isoprenaline
Definition: A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Chemical ID: MESH:D007545
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gata4multiple interactionsEXP 6480464CTDIsoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]PMID:11435416
Gata4multiple interactionsISOGata4 (Mus musculus)6480464CTD[Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNAPMID:10710348
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