Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621157
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Txn1
Name: thioredoxin 1
Acc ID: CHEBI:64211
Term: 8-Br-cAMP
Definition: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase.
Chemical ID: MESH:D015124
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Txn1multiple interactionsEXP 6480464CTD8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in decreased expression of TXN1 protein]PMID:20453393
Go Back to source page   Continue to Ontology report