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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgm2
Name: transglutaminase 2
Acc ID: CHEBI:64210
Term: 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid
Definition: An amidobenzoic acid obtained by formal condensation of the carboxy group of (5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)benzoic acid with the anilino group of 4-aminobenzoic acid. A selective RARalpha agonist.
Chemical ID: MESH:C068073
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgm2increases activityISOTGM2 (Homo sapiens)6480464CTDAm 580 results in increased activity of TGM2 proteinPMID:2884032
Tgm2increases expressionISOTGM2 (Homo sapiens)6480464CTDAm 580 results in increased expression of TGM2 mRNAPMID:16982809
Tgm2multiple interactionsISOTGM2 (Homo sapiens)6480464CTD[Am 580 co-treated with CD 2425] results in increased activity of TGM2 proteinPMID:9516142
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