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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:64163
Term: diquat
Definition: The organic cation formed formally by addition of an ethylene bridge between the nitrogen atoms of 2,2'-bipyridine. Most often available as the dibromide.
Chemical ID: MESH:D004178
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDDiquat results in decreased expression of BCL2 proteinPMID:29484840
Bcl2affects expressionISOBcl2 (Mus musculus)6480464CTDDiquat affects the expression of BCL2 mRNAPMID:26785375 PMID:27057282
Bcl2multiple interactionsISOBcl2 (Mus musculus)6480464CTDprocyanidin B2 affects the reaction [Diquat affects the expression of BCL2 mRNA]PMID:27057282
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