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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2845
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Htr1a
Name: 5-hydroxytryptamine receptor 1A
Acc ID: CHEBI:64123
Term: NAN 190 hydrobromide
Definition: A hydrobromide obtained by reaction of NAN 190 with one equivalent of hydrobromic acid.
Chemical ID: MESH:C058895
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Htr1amultiple interactionsEXP 6480464CTD[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to SerotoninPMID:16528294
Htr1amultiple interactionsISOHtr1a (Mus musculus)6480464CTD[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to MethamphetaminePMID:15213358
Htr1amultiple interactionsISOHTR1A (Homo sapiens)6480464CTD1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A proteinPMID:15482641
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