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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620416
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dnm1l
Name: dynamin 1-like
Acc ID: CHEBI:641
Term: N-methyl-4-phenylpyridinium
Definition: A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.
Chemical ID: MESH:D015655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnm1laffects expressionISODnm1l (Mus musculus)6480464CTD1-Methyl-4-phenylpyridinium affects the expression of DNM1L proteinPMID:33472166
Dnm1lincreases expressionISODNM1L (Homo sapiens)6480464CTD1-Methyl-4-phenylpyridinium results in increased expression of DNM1L; 1-Methyl-4-phenylpyridinium results in increased expression of DNM1L proteinPMID:21615675 PMID:33472166
Dnm1lmultiple interactionsISODNM1L (Homo sapiens)6480464CTD3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone affects the reaction [STUB1 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DNM1L protein]]; 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DNM1L protein]; DNM1L protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; STUB1 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DNM1L protein]; STUB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DNM1L protein]PMID:31253394 PMID:33472166
Dnm1lmultiple interactionsISODnm1l (Mus musculus)6480464CTDSTUB1 protein affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of DNM1L protein]PMID:33472166
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