GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tlr4 | increases expression | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased expression of TLR4 protein | PMID:34481870 | Tlr4 | increases expression | ISO | Tlr4 (Mus musculus) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased expression of TLR4 mRNA; 1-Methyl-4-phenylpyridinium results in increased expression of TLR4 protein | PMID:26881113 PMID:31299241 | Tlr4 | multiple interactions | ISO | TLR4 (Homo sapiens) | 6480464 | CTD | genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TLR4 protein]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of and results in increased activity of CASP3 protein]]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of MYD88 protein]]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of PTGS2 protein]]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of IL1B protein]]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of IL6 protein]]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of TNF protein]] | PMID:34481870 | Tlr4 | multiple interactions | ISO | Tlr4 (Mus musculus) | 6480464 | CTD | TLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of IL1B protein]; TLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of NOS2 protein]; TLR4 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of TNF protein] | PMID:26881113 | |
Go Back to source page | Continue to Ontology report |