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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:64090
Term: tert-butyl hydroperoxide
Definition: An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes.
Chemical ID: MESH:D020122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11affects localizationEXP 6480464CTDtert-Butylhydroperoxide affects the localization of ABCB11 proteinPMID:16452108
Abcb11multiple interactionsEXP 6480464CTD1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCB11 protein]; Bilirubin analog inhibits the reaction [tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCB11 protein]; Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCB11 protein]; tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCB11 proteinPMID:16452108 PMID:24306262
Abcb11decreases expressionISOABCB11 (Homo sapiens)6480464CTDtert-Butylhydroperoxide results in decreased expression of ABCB11 mRNAPMID:34767876
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