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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2857 Species: Rattus norvegicus RGD Object: Gene Symbol: Icam1 Name: intercellular adhesion molecule 1

Acc ID: CHEBI:64019 Term: 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol] Definition: A member of the class of chromanes that is 2,2'-iminodiethanol in which one hydrogen attached to each hydroxy-bearing carbon is replaced by a 6-fluorochroman-2-yl group. CasRN: 99200-09-6 Chemical ID: MESH:C052753

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:69659	6480464	CTD	nebivolol results in decreased expression of ICAM1 mRNA	PMID:17310107