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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stat3
Name: signal transducer and activator of transcription 3
Acc ID: CHEBI:63948
Term: trimethyltin
Definition: An organotin compound that consists of stannane in which three of the four hydrogens are substituted by methyl groups.
Chemical ID: MESH:C046488
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat3increases expressionISOStat3 (Mus musculus)6480464CTDtrimethyltin results in increased expression of STAT3 mRNA; trimethyltin results in increased expression of STAT3 proteinPMID:21435392
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