Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621375
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ikbkb
Name: inhibitor of nuclear factor kappa B kinase subunit beta
Acc ID: CHEBI:63892
Term: zerumbone
Definition: A sesquiterpenoid and cyclic ketone that is (1E,4E,8E)-alpha-humulene which is substituted by an oxo group at the carbon atom attached to two double bonds. It is obtained by steam distillation from a type of edible ginger, Zingiber zerumbet Smith, grown particularly in southeast Asia.
Chemical ID: MESH:C403304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkbmultiple interactionsISOIKBKB (Homo sapiens)6480464CTDzerumbone inhibits the reaction [TNF protein results in increased activity of IKBKB protein]PMID:16007145
Go Back to source page   Continue to Ontology report