Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	621619
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Keap1
Name:	Kelch-like ECH-associated protein 1

Acc ID:	CHEBI:6375
Term:	lansoprazole
Definition:	A sulfoxide that has formula C16H14F3N3O2S.
Chemical ID:	MESH:D064747

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Keap1	increases oxidation	EXP		6480464	CTD	Lansoprazole results in increased oxidation of KEAP1 protein	PMID:19628634

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.