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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61855
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabra1
Name: gamma-aminobutyric acid type A receptor subunit alpha 1
Acc ID: CHEBI:63041
Term: manganese(II) chloride
Definition: An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Chemical ID: MESH:C025340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra1decreases expressionEXP 6480464CTDmanganese chloride results in decreased expression of GABRA1 mRNAPMID:18771689
Gabra1increases expressionEXP 6480464CTDmanganese chloride results in increased expression of GABRA1 proteinPMID:18771689
Gabra1multiple interactionsEXP 6480464CTD[Iron deficiency co-treated with manganese chloride] results in increased expression of GABRA1 proteinPMID:18771689
Gabra1multiple interactionsISOGABRA1 (Homo sapiens)6480464CTD[manganese chloride results in increased abundance of Manganese] which results in decreased expression of GABRA1 proteinPMID:32659473
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