GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases expression | EXP | | 6480464 | CTD | manganese chloride results in increased expression of IL1B protein | PMID:18836210 | Il1b | multiple interactions | EXP | | 6480464 | CTD | [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of IL1B protein] | PMID:18836210 PMID:33314588 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | manganese chloride results in decreased expression of IL1B mRNA | PMID:27427241 | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | manganese chloride results in increased expression of IL1B mRNA | PMID:28539244 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | [Lipopolysaccharides co-treated with manganese chloride] results in increased expression of IL1B protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA] | PMID:15601679 PMID:28539244 PMID:34018660 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA; [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B protein | PMID:28539244 | |
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