GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735440
Species: Homo sapiens
RGD Object: Gene
Symbol: NFKBIA
Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Acc ID: CHEBI:61668
Term: oroxylin A
Definition: A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-6.
CasRN: 480-11-5
Chemical ID: MESH:C080669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:109756480464CTD5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]

PMID:22101131
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