• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732416 Species: Homo sapiens RGD Object: Gene Symbol: RPE65 Name: retinal pigment epithelium-specific protein 65kDa

Acc ID: CHEBI:6067 Term: isotretinoin Definition: A retinoic acid that has formula C20H28O2. CasRN: 4759-48-2 Chemical ID: MESH:D015474

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:2319763	6480464	CTD	[Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde	PMID:16411761
multiple interactions	ISO	RGD:732417	6480464	CTD	[Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde	PMID:16411761
multiple interactions	ISO	RGD:621396	6480464	CTD	[Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde	PMID:16411761
multiple interactions	ISO		6480464	CTD	[Isotretinoin binds to and results in decreased activity of RPE65 protein] which results in decreased abundance of Retinaldehyde	PMID:16411761