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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3732
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2
Acc ID: CHEBI:6015
Term: isoflurane
Definition: An organofluorine compound that has formula C3H2ClF5O.
Chemical ID: MESH:D007530
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2multiple interactionsEXP 6480464CTD5-hydroxydecanoic acid inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein]; Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein; tempol inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein]PMID:17693941
Sod2decreases activityISOSod2 (Mus musculus)6480464CTDIsoflurane results in decreased activity of SOD2 proteinPMID:23922164
Sod2multiple interactionsISOSod2 (Mus musculus)6480464CTDresveratrol inhibits the reaction [Isoflurane results in decreased activity of SOD2 protein]PMID:23922164
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