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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2926
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgam
Name: integrin subunit alpha M
Acc ID: CHEBI:6015
Term: isoflurane
Definition: An organofluorine compound that has formula C3H2ClF5O.
Chemical ID: MESH:D007530
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgamdecreases expressionISOItgam (Mus musculus)6480464CTDIsoflurane results in decreased expression of ITGAM proteinPMID:28003439
Itgammultiple interactionsISOItgam (Mus musculus)6480464CTDIsoflurane inhibits the reaction [ITGAM protein binds to ICAM1 protein]PMID:28003439
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