GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases expression | EXP | | 6480464 | CTD | Isoflurane results in increased expression of IL1B mRNA; Isoflurane results in increased expression of IL1B protein | PMID:10422944 PMID:28084090 PMID:35164634 | Il1b | multiple interactions | EXP | | 6480464 | CTD | MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]; MIR7-1 mRNA affects the reaction [MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]]; rhodioloside inhibits the reaction [Isoflurane results in increased expression of IL1B protein] | PMID:28084090 PMID:35164634 | Il1b | decreases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Isoflurane results in decreased expression of IL1B mRNA | PMID:17414419 | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Isoflurane results in increased expression of IL1B protein | PMID:35164634 PMID:35187972 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | MEG3 mRNA affects the reaction [Isoflurane results in increased expression of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Isoflurane results in increased expression of IL1B protein]; SETD7 protein affects the reaction [Isoflurane results in increased expression of IL1B protein] | PMID:35164634 PMID:35187972 | | ||||||||||||||||||||||
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