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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl5
Name: C-C motif chemokine ligand 5
Acc ID: CHEBI:59750
Term: diflorasone
Definition: The 16beta-analogue of flumethasone. It is used as the 17,21-diacetate as a topical anti-inflammatory and antipruritic in the treatment of various skin disorders.
Chemical ID: MESH:C014477
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl5multiple interactionsISOCcl5 (Mus musculus)6480464CTDdiflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL5 protein]; diflorasone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein]PMID:15491423
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