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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3935
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase family 1 member A1
Acc ID: CHEBI:5885
Term: imperatorin
Definition: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.
Chemical ID: MESH:C031534
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a1multiple interactionsEXP 6480464CTDimperatorin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin]PMID:17599282
Ugt1a1multiple interactionsISOUGT1A1 (Homo sapiens)6480464CTDimperatorin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Bilirubin]PMID:17599282
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