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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3776 Species: Rattus norvegicus RGD Object: Gene Symbol: Sult1e1 Name: sulfotransferase family 1E, estrogen-preferring, member 1

Acc ID: CHEBI:5855 Term: ibuprofen Definition: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. CasRN: 15687-27-1 Chemical ID: MESH:D007052

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:1351097	6480464	CTD	Ibuprofen results in decreased activity of SULT1E1 protein	PMID:17073578