GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | increases expression | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Ibuprofen results in increased expression of CCL2 mRNA | PMID:17070997 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Ibuprofen inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Ibuprofen inhibits the reaction [IL1B protein results in increased expression of CCL2 protein] | PMID:18799549 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Ibuprofen inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] | PMID:11230753 | |
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