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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:5835
Term: hypericin
Definition: A carbopolycyclic compound that has formula C30H16O8.
Chemical ID: MESH:C004965
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases expressionISOABCB1 (Homo sapiens)6480464CTDhypericin results in increased expression of ABCB1PMID:16005588
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDhypericin inhibits the reaction [ABCB1 protein results in increased secretion of Ritonavir]PMID:15266218
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