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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317190 Species: Homo sapiens RGD Object: Gene Symbol: POLE4 Name: polymerase (DNA-directed), epsilon 4, accessory subunit

Acc ID: CHEBI:5775 Term: hydralazine Definition: The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent. CasRN: 86-54-4 Chemical ID: MESH:D006830

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[Hydralazine co-treated with Valproic Acid] results in increased expression of POLE4 mRNA	PMID:17183730