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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621414
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: CHEBI:5543
Term: Grepafloxacin
Definition: A fluoroquinolone antibiotic that has formula C19H22FN3O3.
Chemical ID: MESH:C075375
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2decreases activityISOKCNH2 (Homo sapiens)6480464CTDgrepafloxacin results in decreased activity of KCNH2 proteinPMID:21158687
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