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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562975
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdm1a
Name: lysine demethylase 1A
Acc ID: CHEBI:53662
Term: biguanides
Definition: A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Chemical ID: MESH:D001645
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdm1adecreases activityISOKDM1A (Homo sapiens)6480464CTDBiguanides analog results in decreased activity of KDM1A proteinPMID:17463086
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