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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:53444
Term: potassium dichromate
Definition: A potassium salt that is the dipotassium salt of dichromic acid.
Chemical ID: MESH:D011192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2affects localizationEXP 6480464CTDPotassium Dichromate affects the localization of BCL2 proteinPMID:21262251
Bcl2decreases expressionEXP 6480464CTDPotassium Dichromate results in decreased expression of BCL2 proteinPMID:21262251 PMID:25245570 PMID:26348139 PMID:37931768
Bcl2multiple interactionsEXP 6480464CTD[6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide co-treated with [Potassium Dichromate results in increased abundance of chromium hexavalent ion]] results in decreased expression of BCL2 protein; [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of BCL2 protein; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]PMID:21262251 PMID:25245570 PMID:30974164 PMID:35307491 PMID:36849043
Bcl2decreases expressionISOBcl2 (Mus musculus)6480464CTDPotassium Dichromate results in decreased expression of BCL2 proteinPMID:19219935
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