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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:53351
Term: chromium(3+) trichloride
Definition: A chromium chloride with the chromium cation in the +3 oxidation state.
Chemical ID: MESH:C022990
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2increases expressionISOCCL2 (Homo sapiens)6480464CTDchromic chloride results in increased expression of CCL2 proteinPMID:23629852
Ccl2multiple interactionsISOCcl2 (Mus musculus)6480464CTD[cobaltous chloride co-treated with chromic chloride] results in increased expression of CCL2 mRNAPMID:25966675
Ccl2multiple interactionsISOCCL2 (Homo sapiens)6480464CTDchromic chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]PMID:17665966
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