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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732177 Species: Mus musculus RGD Object: Gene Symbol: Cxcr4 Name: chemokine (C-X-C motif) receptor 4

Acc ID: CHEBI:53076 Term: 4-(ethoxymethylene)-2-phenyloxazol-5-one Definition: A 1,3-oxazole compound having a phenyl substituent at the 2-position, an ethoxymethylene group at the 4-position, and an oxo group at the 5-position. CasRN: 15646-46-5 Chemical ID: MESH:D010081

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Oxazolone results in decreased expression of CXCR4 mRNA	PMID:11379042
increases expression	ISO	RGD:732176	6480464	CTD	Oxazolone results in increased expression of CXCR4 mRNA	PMID:17374397