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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303089 Species: Rattus norvegicus RGD Object: Gene Symbol: Gsn Name: gelsolin

Acc ID: CHEBI:53063 Term: 2,4,6-trinitrobenzenesulfonic acid Definition: A benzenesulfonic acid compound with three nitro substituents in the 2-, 4- and 6-positions. CasRN: 2508-19-2 Chemical ID: MESH:D014302

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1550660	6480464	CTD	Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA]	PMID:18200517
decreases expression	ISO	RGD:1550660	6480464	CTD	Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA	PMID:18200517 PMID:17982090
decreases expression	ISO	RGD:1550660	6480464	CTD	Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA	PMID:17982090 PMID:18200517