GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
730895
Species:
Mus musculus
RGD Object:
Gene
Symbol:
Il18
Name:
interleukin 18
Acc ID:
CHEBI:53053
Term:
1-chloro-2,4,6-trinitrobenzene
Definition:
A chlorobenzene compound with three nitro substituents in the 2-, 4- and 6-positions.
CasRN:
88-88-0
Chemical ID:
MESH:D010853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
multiple interactions ISO RGD:730894 6480464 CTD CASP1 protein promotes the reaction [Picryl Chloride results in increased cleavage of IL18 protein] PMID:17429439 increases cleavage ISO RGD:730894 6480464 CTD Picryl Chloride results in increased cleavage of IL18 protein PMID:17429439 multiple interactions EXP 6480464 CTD Cyclosporine inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] Rolipram inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] PMID:16442096 increases expression EXP 6480464 CTD Picryl Chloride results in increased expression of IL18 protein PMID:16442096 PMID:15734285 increases expression EXP 6480464 CTD Picryl Chloride results in increased expression of IL18 protein PMID:15734285 PMID:16442096 multiple interactions EXP 6480464 CTD anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Picryl Chloride results in increased secretion of IL18 protein] anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Picryl Chloride results in increased expression of IL18 mRNA] PMID:20381601 increases expression EXP 6480464 CTD Picryl Chloride results in increased expression of IL18 mRNA PMID:20381601 increases secretion EXP 6480464 CTD Picryl Chloride results in increased secretion of IL18 protein PMID:20381601