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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621805
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b3
Name: hydroxysteroid (17-beta) dehydrogenase 3
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b3decreases expressionEXP 6480464CTDnickel sulfate results in decreased expression of HSD17B3 mRNAPMID:29567110
Hsd17b3multiple interactionsEXP 6480464CTD[CGA protein co-treated with nickel sulfate] results in decreased expression of HSD17B3 mRNA; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; pyrazolanthrone inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; SB 203580 inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]; U 0126 inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]PMID:29567110
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